Medication Alert: Major changes to Sinemet and Levocarb

If you take Sinemet or the generic form Levocarb, please be aware that, over the past 18 months,

  • the supply of Sinemet and Levocarb has changed;
  • the markings on the Sinemet CR (controlled release) and Sinemet IR (immediate release) pills have also changed. These changes include new colours, shapes, markings, non-medicinal ingredients and storage conditions. The changes also affect how people take the drug and how physicians prescribe it, as the newly marked pills are no longer scored for splitting.For full details, visit parkinson.ca and read Medication – Sinemet changes.

3 Responses to “Medication Alert: Major changes to Sinemet and Levocarb”


  1. 1 Maisie Harrison August 14, 2011 at 2:33 pm

    Was taking Sinemet CR 100/25 and Sinemet 100/25 : One tablet of each, 6 times a day, with good results. Began having reactions once the new CR tablet was introduced- increasingly severe constant headache- balance deteriation, also hand co-ordination-some depression- right leg muscles painful and stiff.
    Dr. Adams prescribed Prolopa 100/25 100mg. & 25mg.
    Levodopa & Benserazide
    Taking this for 15 days now, and am feeling very much improved.

  2. 2 Parkinson Society Canada September 20, 2011 at 3:15 pm

    Thank you for your comment. For more information about Medication, please visit the Resources page or Medication information page of our website.

  3. 3 Rochelle Paul April 21, 2014 at 11:00 pm

    I’d like to know if Levocarb can also used for leg cramps.


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All material related to Parkinson's disease contained in Parkinson Post is solely for the information of the reader. It should not be used for treatment purposes. Specific articles reflect the opinion of the writer and are not necessarily the opinion of PSC.

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