Sinemet: brand/generic cost difference covered by Merck

If you have been prescribed Sinemet or Sinemet CR, please note that on November 7, 2011, Merck Canada Inc., the manufacturer of Sinemet, launched a program that will pay the difference in cost between the generic and brand-name product.

To participate, request a Sinemet Patient Assistance Program card from either your neurologist (who can get a supply of cards for patients) or directly from Merck. Then, present the card to the pharmacist when you are seeking a refill or requesting a new prescription for Sinemet or Sinemet CR. Request “no substitution.”

The pharmacist will fill the prescription with the brand product but bill you the cost of the generic. Merck will pay the pharmacy the difference in cost. You should retain the card and use it as long as your prescription continues.

For more information about the Sinemet Patient Assistance Program, see the letter from Merck Canada or contact your regional Parkinson Society.

4 Responses to “Sinemet: brand/generic cost difference covered by Merck”


  1. 1 Arlene Klein August 6, 2012 at 2:08 pm

    Is there a comparable program for people in the US? Would rather have Merck than generic.

  2. 2 Parkinson Society Canada August 10, 2012 at 1:06 pm

    Our scope covers Canada only so we cannot confirm if such a program exists in the U.S. You may wish to check out http://www.merck.com and of course, please check with your doctor also.

  3. 3 Linda McDaniel April 30, 2013 at 1:09 am

    My husband has had Parkinson since 1992. He was prescribed Sinemet
    Brand. In the last few years we have had to order brand and wait a
    considerable time for brand. IT IS MUCH MORE EXPENSIVE.
    Our Doctor Richard Caviness at Mayo Clinic prescribed brand in the
    beginning. I have stuck to BRAND even though I wonder if it has been
    changed recently as it does not seem to work as well as in the beginning.

    Is Merch-Shar 25/100 the same as in 1992?? Or, has it been generic
    and we are paying for brand?? I always ask Walgreen Drug for brand.

    Thank you.

    Linda McDaniel

  4. 4 Parkinson Society Canada April 30, 2013 at 11:10 am

    Hello Linda, Thank you for your enquiry. As you are based in the US, it would be best to check with the pharmacist or your husband’s physician.


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All material related to Parkinson's disease contained in Parkinson Post is solely for the information of the reader. It should not be used for treatment purposes. Specific articles reflect the opinion of the writer and are not necessarily the opinion of PSC.

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